| Experimental Days | ||||
| Treatment | Day 1 | Days 2-6 | Days 7-9 | Day 10 |
| Saline | Saline/Saline | Saline | Washout | Saline/Saline |
| 0.6 mg/kg MPD | Saline/0.6 mg/kg | 0.6 mg/kg MPD | Washout | Saline/0.6 mg/kg |
| 2.5 mg/kg MPD | Saline/2.5 mg/kg | 2.5 mg/kg MPD | Washout | Saline/2.5 mg/kg |
| 5.0 mg/kg MPD | Saline/5.0 mg/kg | 5.0 mg/kg MPD | Washout | Saline/5.0 mg/kg |
| 10.0 mg/kg MPD | Saline/10.0 mg/kg | 10.0 mg/kg MPD | Washout | Saline/10.0 mg/kg |